Coronary artery disease, Chronic kidney, disease, Hypertension, Diabetes mellitus
Conditions
Interventions
Patients with coronary artery disease, patients having atherosclerotic risks, Normal individual
Sponsors
Hokkaido University Graduate School of Medicine,
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Patients with CAD (coronary artery disease) or suspected CAD. 2.Patient have risk of atherosclerosis , such as hypertension, DM (Diabetes Mellitus), kidney disease and smoker.
Exclusion criteria
Exclusion criteria: 1.Advanced AV block 2.Bronchial asthma 3.Pregnant women 4.Subjects who will not be able to obtain written informed concent. 5.Others who physicians will consider the contraindication for the participation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The association between brachial artery diameter ,FMD measured by ultrasound, and MBF (myocardial Blood Flow) at rest, ATP(adenosinetriphosphate) stress and, CPT (Cold Pressor Test) stress. CFR(coronary flow reserve), CPT response evaluated by 3D PET/CT will also be compared to FMD and NTG response. | — |
Secondary
| Measure | Time frame |
|---|---|
| The association between vascular elasticity,brachial arterial diameter measured by automated oscillometric method and brachial diameters and artery function measured by brachial artery ultrasound. | — |
Countries
Japan
Contacts
Public ContactYoshinaga, M.D., Ph.D, F.A.C.C.
Hokkaido University Graduate School of Medicine Department of molecular imaging
Outcome results
None listed