Squamous cell carcinoma of oral cavity
Conditions
Interventions
Surgical procedure Selective neck dissection (level I-IV) is performed in accordance with standard functional neck dissection. Internal jugular vein, spinal accessory nerve and sternocleidomastoid m
1) Level Ia is included when the primary site is located lip, anterior portion of oral floor and oral tongue and lower gum between both canine. 2) Level IIb is included when there are metastases in
1) when extracapsular spreading is observed 2) when more than 3 metastatic lymph nodes are observed. The extent of postoperative irradiation includes level I-V.
Sponsors
Osaka University Graduate School of Dentistry Oral Cancer Treatment Group
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) clinical N+ case (using CT, MRI, ECHO and PET) (2) N stage: N1, N2a, N2b or N2c and no fixed lymph nodes (3) No metastatic lymph nodes in level V (4) Primary sites are lip, mobile tongue, oral floor, gingival and buccal mucosa (no infiltration into oropharyngeal). (5) More than 18 year old (6) No systemic problem (7) PS 0-1 (ECOG) (8)
Exclusion criteria
Exclusion criteria: (1)Cases who do not meet the inclusion criteria (2)Cases who judges improper for level I-IV dissection by surgeon during operation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prognosis 1)regional recurrence 2)rate of regional control 3)survival rate Functional disorders 1)function of spinal accessory nerve 2)uncomfortable symptom of neck (pain,limitation of movement , etc) | — |
Countries
Japan
Contacts
Public ContactMitsuhiro Nakazawa
Osaka University Dental Hospital 2nd Department of Oral and Maxillofacial Surgery
Outcome results
None listed