Esophageal cancer
Conditions
Interventions
Elental
Control
Sponsors
Chiba University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.The primary tumor is located within the neck, the chest or the abdominal esophagus. 2. Pathologically proven squamous, adenosquamous or adenocarcinoma. 3. Stage 0-IV 4. 20 years old or more. 5. ECOG PS2 or less. 6. Without brain metastases. 7. Without pleural effusion, ascites. 8. Elemental diet can be administered orally or by tube feeding. 9. Naive for chemotherapy or 1 or more months have been passed after prior chemotherapy. 10. Patients underwent oral care with explamation of oral hygene. 11. Informed consent is obtained.
Exclusion criteria
Exclusion criteria: 1. Diabetes Mellitus which requires continuous insulin administration. 2. Active double cancers. 3. Hypersensitivity for CDDP, leucovorin and 5-FU. 4. Contraindication of elental. 5. Active infections. 6. Continuous administration of steroids. 7. Neural paralysis (CTCAE v4.0 Grade1 or more). 8. Edema(CTCAEv4.0 Grade1 or more). 9. Plumonary fibrosis, pneumonitis. 10. psycholotical issues. 11. Patients enrolled in other clinical trials in which the endpoints are same. 12. Pregnant patients. 13. Inappropriate patients that doctors judged.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The rate of oral mucositis | — |
Countries
Japan
Contacts
Public ContactYasunori Akutsu
Chiba University Department of Frontier Surgery
Outcome results
None listed