Optimization of the scan timing after Gd contrast media injection in the detection of brain metastases-Multicenter study-

Optimization of the scan timing after Gd contrast media injection in the detection of brain metastases-Multicenter study- - The optimal interval after Gd injection for MRI of brain metastases

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000014594

Enrollment

600

Registered

2014-09-01

Start date

2014-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Brain metastases

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who meet all the following criteria can be included in the study 1) Patients who had undergone Gd-enhanced brain MRI in the past 3 years (dose: 0.1 mmol/kg) 2) Patients who had undergone contrast-enhanced T1-weighted SE images more than once 3) The time between injection of contrast agent and imaging can be estimated by minutes 4) Lesion size: 3 to 20 mm 5) Both inpatient and outpatient 6) Aged 20 years or older

Exclusion criteria

Exclusion criteria: Patients who meet any of the following criteria are not eligible for the study 1) Patients with bleeding that may affect measurement of the signal intensity 2) The signal intensity cannot be measured 3) Patients with 10 or more lesions 4) Patients who have already enrolled in the present study

Design outcomes

Primary

Measure	Time frame
The detection rate of metastatic brain tumor by subjective evaluation of images	—

Secondary

Measure	Time frame
The signal intensity ratio of metastatic brain tumor against the surrounding brain parenchyma	—

Countries

Japan

Contacts

Public ContactKouhei Kamiya

The University of Tokyo Hospital Department of Radiology

kkamiya-tky@umin.ac.jp03-5800-8666

Outcome results