Age-dependent change of the minimum alveolar concentrations of desflurane for maintaining bispectral index below 50

Age-dependent change of the minimum alveolar concentrations of desflurane for maintaining bispectral index below 50 - Advance of age and requirement of desflurane

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000014592

Enrollment

Registered

2014-07-20

Start date

2014-07-22

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Deseases requiring surgical treatment under general anesthesia

Interventions

Measuring bispectral index after administrating desflurane for maintaining the end-tidal concentration at a fixed level in patients between 20 and 30 years old undergoing general anesthesia. Measuring

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients undergoing general anesthesia under tracheal intubation with American Society of Anesthesiologists physical status I or II

Exclusion criteria

Exclusion criteria: Patients with bronchial asthma, arrhythmia, psychiatric disorder, ischemic heart diseases, low cardiac output with ejection fraction equal to or less than 40%, systolic blood pressure below 80 mmHg or abnormal serum electrolytes

Design outcomes

Primary

Measure	Time frame
Differences of the alveolar concentration of desflurane for maintaining bispectral index below 50 (MACBIS 50) among different age groups	—

Countries

Japan

Contacts

Public ContactYutaka Oda

Osaka City General Hospital and Children's Hospital Department of Anesthesiology

odayou@s5.dion.ne.jp06-6929-1221

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026