Postoperative pain was successfully treated with 8 mcg/kg of transitional fentanyl following high dose remifentanil anesthesia.

Postoperative pain was successfully treated with 8 mcg/kg of transitional fentanyl following high dose remifentanil anesthesia. - Postoperative pain was successfully treated with 8 mcg/kg of transitional fentanyl following high dose remifentanil anesthesia.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000014565

Enrollment

Registered

2014-09-01

Start date

2011-09-02

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

jaw deformity

Interventions

Administration of 1 mcg/kg/min of remifentanil combined with 4 mcg/kg transitional fentanyl. Administration of 1 mcg/kg/min of remifentanil combined with 8 mcg/kg transitional fentanyl.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients who undergoing orthognathic surgery were included in this study. American Society of Anesthesiologists (ASA) physical status I-II.

Exclusion criteria

Exclusion criteria: they had obesity (body mass index over 30 kg/m2); could not be extubated immediately after surgery; had been treated any analgesic drug within 24 hours prior to surgery; had a history of chronic pain, drug or alcohol abuse, or psychiatric disease; and had contraindications to the self-administration of opioids [i.e. they were unable to understand the patient-controlled analgesia (PCA) device].

Design outcomes

Primary

Measure	Time frame
Amount of fentanyl administered within 24 hours after surgery. Visual analog scale (VAS) values at 1, 3, 6, and 24 hours after surgery.	—

Secondary

Measure	Time frame
Estimated effect-site concentrations of both fentanyl and remifentanil at extubation. Time from the completion of surgery to the extubation. Side-effects.	—

Countries

Japan

Contacts

Public ContactKyotaro Koshika

Tokyo Dental College Ichikawa General Hospital Department of Anesthesiology

koshikakyotarou@tdc.ac.jp047-322-0151

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026