The effects of polymyxin B hemoperfusion on extra vascular lung water and pulmonary vascular permeability

The effects of polymyxin B hemoperfusion on extra vascular lung water and pulmonary vascular permeability - The effects of polymyxin B hemoperfusion on extra vascular lung water and pulmonary vascular permeability

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000014546

Enrollment

Registered

2014-07-13

Start date

2014-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastrointestinal perforation

Interventions

Insert catheters for VolumeView and FloTrac sensor, vascular access for direct hemoperfusion, either in operation rooms or intensive care unit. Cables are connected to EV1000 Clinical Platform (Edward

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients treated with PMX-DHP after gastrointestinal surgery

Exclusion criteria

Exclusion criteria: Severe respiratory disease, including patients with dissected lungs

Design outcomes

Primary

Measure	Time frame
Extra vascular lung water and pulmonary vascular permeability before, during and after PMX-DHP	—

Secondary

Measure	Time frame
Serum cytokine levels before, during and after PMX-DHP	—

Countries

Japan

Contacts

Public ContactTasuku Yoshida

Yokohama City University Department of Anesthesiology and Critical Care Medicine

ytasuku@yokohama-cu.ac.jp045-787-2918

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026