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The investigation of the association of low-dose aspirin and reflux esophagitis

The investigation of the association of low-dose aspirin and reflux esophagitis - The investigation of the association of low-dose aspirin and reflux esophagitis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000014543
Enrollment
200
Registered
2014-07-14
Start date
2014-04-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Reflux esophagitis

Interventions

We let reflux esophagitis patients take esomeprazole 20mg/day for 8 weeks

Sponsors

Oita university, department of Gastroenterology
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The patients who diagnosed as reflux esophagitis, Los Angeles classification, grade A, B, C, or D, by esophagogastroduodenoscopy

Exclusion criteria

Exclusion criteria: 1. Patients with active gastric ulcer or duodenal ulcer. 2. Patients with hypersensitivity to esomeprazole. 3. Patients in the administration of atazanavir sulfate or a Rirupibirin hydrochloride. 4. Patients with chronic alcoholism or drug dependence. 5. Patients with warning symptoms, such as vomitting, or sudden weight loss. 6. The patient who has difficulty in participation in this examination by the mergers such as a serious liver disease, renal disease, or heart trouble. 7. Pregnant women, nursing girls or the women who may be pregnant. 8. Patients who judged unsuitable for research participation.

Design outcomes

Primary

MeasureTime frame
The risk odds ratio of the low-dose aspirin for the reflux esophagitis onset

Secondary

MeasureTime frame
The rate that reflux esophagitis improves by proton pump inhibitor administration

Countries

Japan

Contacts

Public ContactKazuhiro Mizukami

Oita university Department of Gastroenterology

mizkaz0809@oita-u.ac.jp097-586-6193

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026