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To evaluate the mechanism of anti TSH-receptor antibody production in patients with untreated Graves' disease.

To evaluate the mechanism of anti TSH-receptor antibody production in patients with untreated Graves' disease. - To evaluate the mechanism of anti TSH-receptor antibody production in patients with untreated Graves' disease.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000014527
Enrollment
30
Registered
2014-07-14
Start date
2014-09-01
Completion date
Unknown
Last updated
2025-07-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Graves&#39

Interventions

To isolate B cell from whole blood sample from patients with untreated Graves&#39
disease.

Sponsors

Departments of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria:

Exclusion criteria

Exclusion criteria: 1) Patients with congenital immunodeficiency. 2) Patients who are treated with immunosuppressant or biologics. 3) Patients with other autoimmune disease or chronic inflammatory disease. 4) Pregnant or lactating women. 5) Patients who are at the age of <20y.o. or >=80y.o. 6) Patients who lack judgment to attend this study in social or medical aspect. 7) Patients who disagree with this study.

Design outcomes

Primary

MeasureTime frame
Anti TSH-receptor antibody production from isolated B cell of patients with untreated Graves disease are stimulated by verious factors.—

Countries

Japan

Contacts

Public ContactToyoyoshi Uchida

Juntendo University Graduate School of Medicine Departments of Metabolism & Endocrinology

uchitoyo@juntendo.ac.jp03-5802-1579

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Feb 4, 2026