Lung cancer Neuropathic Pain Postoperative shoulder pain
Conditions
Interventions
Patients received pregabalin 150 mg po 10-16 h after surgery and then non-steroidal anti-inflammatory drugs (NSAIDs) po 2 hours later. (maximum dose is 300 mg/day)
only NSAIDs po (loxoprofen 180mg/da
Sponsors
Akita University Graduate School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Histologically or cytologically confirmed lung cancer 2)without indication for curative radiation therapy 3)Performance Status(ECOG) 0-1 4)Patients aged 20 years or older 5)Sufficient function of main organ and normal hematopoietic function, normal liver function and normal renal function filled the following criteria *Leukocyte counts >= 3,000/mm3 *Neutrophil counts >= 1,500/mm3 *Platelets >= 100,000/mm3 *Hemoglobin concentration >= 9.0 g/dL *AST and ALT, x 2.5 of upper limit of normal (ULN) or less. *Total bilirubin <=1.5mg/dL. *Serum creatinin, x 1.5 of ULN or less. *Electrocardiogram Nomal *SpO2 >=90% or SaPO2 >=65mmHg *Protein urea >= 1+ 6)Patients providing written informed consent
Exclusion criteria
Exclusion criteria: Inappropriate patients for this study judged by the physicians
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Shoulder pain severity was measured using a 100-mm visual analog scale (VAS) scoring system until post operative days 7. | — |
Countries
Japan
Contacts
Public ContactKazuhiro Imai
Akita University Graduate School of Medicine General Thoracic Surgery (and Breast & Endocrine Surgery)
Outcome results
None listed