Resectable colorectal cancer with hepatic metastasis
Conditions
Interventions
UFT/UZEL
Sponsors
Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Colorectal cancer is hitologically diagnosed 2. Synchronous or metachronous liver metastasis is diagnosed 3. There are no distant metastasis, recurrence except liver on CT within 4 weeks before liver resection 4. Curative resection (R0)is performed 5. The age is between 20 years old and 80 years old at the registration day. 6. Performance status is 0-2 cases. 7. The oral intake of the drug is possible. 8. A major organ function is maintained by a laboratory study within 14 days before registration. 9. An agreement is obtained in a document from the patients.
Exclusion criteria
Exclusion criteria: 1. multiple primary cancer 2. Serious postoperative complications 3. Case with the following complications -Poor control diabetes mellitus -Poor control hypertention -Myocardial infarction or unstable angina within six months. -Interstitial pneumonia, pulmonary fibrosis, severe pulmonary emphysema 4. Case with the following -A pregnant woman or the women who may be pregnant or hope to be pregnant -lactating women 5. The patients complicated with psychosis or neurologic manifestation, and judged to have difficulty in participation in clinical trials. 6. The case judged to be unsuitable for registration
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Disease Free Survival | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall Survival, Relapse Free Survival, Safety, the ratio of the patients who completed the course of UFT/UZEL, Quality of Life | — |
Countries
Japan
Contacts
Public ContactHideki Yokoo
Hokkaido University Graduate School of Medicine Gastroenterological Surgery I
Outcome results
None listed