Intensity modulated radiation therapy for multiple brain metastases

Intensity modulated radiation therapy for multiple brain metastases - Intensity modulated radiation therapy for multiple brain metastases

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000014455

Enrollment

Registered

2014-08-01

Start date

2014-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple brain metastases

Interventions

Whole brain radiation therapy (30Gy in 10 fractions) is delivered with a simultaneous integrated boost of 50Gy to brain metastases.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. MRI confirmed >= 5 brain metastases 2. Life expectancy greater than 3 months 3. Age >= 20 4. Written informed consent 5. Histologically or clinically diagnosed malignant tumor

Exclusion criteria

Exclusion criteria: 1. Rapidly progressive neurological symptom 2. Small cell lung cancer 3. Pregnant or lactating women 4. Previous radiotherapy of the brain 5. MRI contraindication

Design outcomes

Primary

Measure	Time frame
Local control rate, Intracranial progression free survival	—

Secondary

Measure	Time frame
Morbidity, Neurocognitive function	—

Countries

Japan

Contacts

Public ContactShunsuke Furutani

The University of Tokushima Department of Radiology

s.furutani@tokushima-u.ac.jp088-633-7173

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026