The intellectual disabled patients (The patients having a history of showing serious maladaptive behaviors in dentistry within the past one year)
Conditions
Interventions
Oral administration of lorazepam with a dose of 3mg divided in 3 times per day for preoperative 2 days, and a single dose of 1mg on the operative morning 2 hours prior to a general anesthesia or proce
Sponsors
Ogata Pediatric Dental Clinic
Matsushima Mental Clinic
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Intellectually disabled subjects who have a history of difficulty in a dental prcedure including a general anesthesia induce because of their serious maladaptative behavior, within the past one year. 2)Physical constitution of the subjects correspond to the adult size, and therefore a control of behavior with a medicine is essential. 3)Guardians of the subjects consent and cooperate to this study.
Exclusion criteria
Exclusion criteria: 1)Subjects who are contraindicated to benzodiazepine drugs (acute narrow-angle glaucoma, nuero-muscle disease). 2)Consultation is needed about an indication of lorazepam, to a regular doctor if a subject is administered other psychotropic drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The efficacy of lorazepam is assessed on the day of general anesthesia or procedure of dentistry, about 2 hours after the last administration of lorazepam. | — |
Secondary
| Measure | Time frame |
|---|---|
| The anticipated maladaptative behaviors (such as inability of coming to a clinic, inability of entering the operating room, inability of sitting down on a dental chair, or running away ect.) are scored according to the degree of serious level. The scored points corresponding to maladaptative behaviors after lorazepam premedication, are compared with those in the past hitory. | — |
Countries
Japan
Contacts
Public ContactAkiko Shiki DDS
Ogata Pediatric Dental Clinic Dental Anesthesia
Outcome results
None listed