subarachnoid hemorrhage
Conditions
Interventions
Sponsors
Hirosaki University Graduate School of Medicine Department of Neurosurgery
Kuroishi General Hospital Aomori City Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Ruptured aneurysm was secured by clipping or coiling within 24 hours after the onset of SAH, and oral administration of placebo or cilostazol was started within 48 hours after the onset of SAH. 3. SAH should be diffuse or localized thick subarachnoid clot on CT scan performed within 24 hours of SAH. 2. clinical grade evaluated by a World Federation of Neurological Surgeons Grade or Hunt and Hess Grade was 1 to 4 before clipping or coiling.
Exclusion criteria
Exclusion criteria: 1. Pre-existing major hepatic, renal, pulmonary or cardiac disease. 2. prior cerebral damage of past history of stroke or traumatic brain injury confirmed by CT scan. 3. focal neurological deficits on admission due to accompanying intracerebral clot. 4. current use of anti-platelet and/or anticoagulant agent. 5. operative neurological deficits arisen due to clipping or coiling procedure. 6.drug allergy 7. pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| occurrence of symptomatic vasospasm | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) angiographic vasospasm on digital subtraction angiography 2) cerebral infarction due to cerebral vasospasm on CT scan 3) functional outcome (m-RS, GOS) 4) adverse event | — |
Countries
Japan
Contacts
Public ContactMasato Naraoka
Hirosaki University Graduate School of Medicine Department of Neurosurgery
Outcome results
None listed