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The efficacy and safety of a hypertonic polyethylene glycol - electrolyte lavage solution (PEG-ELS) for patients with constipated patients or regularly user of a laxative: a randomized study

The efficacy and safety of a hypertonic polyethylene glycol - electrolyte lavage solution (PEG-ELS) for patients with constipated patients or regularly user of a laxative: a randomized study - The efficacy and safety of a hypertonic polyethylene glycol - electrolyte lavage solution (PEG-ELS).

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000014392
Enrollment
100
Registered
2014-06-26
Start date
2014-07-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with chronic constipation, functional constipation or regularly use of a laxative

Interventions

A hypertonic PEG-ELS is administrated for colonoscopy bowel preparation. A conventional PEG-ELS is administrated for colonoscopy bowel preparation.

Sponsors

Hokkaido University Hospital, Division of Endoscopy
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1)Patients with chronic constipation or functional constipation. (2) 20years or older and up to 80 years old. (3) Patients judged to resect polyp in total colonoscopy within the past two years, and undergoing polypectomy. (4) )Written informed consent obtained.

Exclusion criteria

Exclusion criteria: (1) Patients with a history of gastrointestinal tractresection (excluding appendicectomy) (2) Patients required for colonic ESD (3) Patients who may have ileus (4) Patients who have a history of perforation and may have perforation of gastrointestinal tract (5) Patients with failure of gastric empty (6) Patients with toxic megacolon (7) Patients with a history of hypersensitivity to composition of a PEG-ELS or Moviprep (8) Patients with nausea and vomiting (9) Patients who request to increase dose of a laxative which is taken commonly from obtaining informed consent to the day before preparation (10)Patients who may be admitted for purposes of other than polypectomy (11) Patients who are considered to be unsuitable by the trial investigators

Design outcomes

Primary

MeasureTime frame
The rate of poor colon preparation(Ottawa bowel preparation scale>2) and rate of the patients who needed the enema .

Countries

Japan

Contacts

Public ContactKatsuhiro Mabe

Hokkaido University Hospital Division of Endoscopy

kmabe@med.hokudai.ac.jp+81-11-716-1161

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026