Acute myocardial infarction
Conditions
Interventions
Patients who diagnose that they are having an acute myocardial infarction at a cardiovascular angiogram room start to inhale gas and continue to inhale gas during PCI procedure.
Control group: contro
Sponsors
National Center for Global Health and Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: ST-segment elevation myocardial infarction within 12hours following the onset of chest pain
Exclusion criteria
Exclusion criteria: Shock (BP<90mmHg) Patient of Congestive Heart Failure or Severe hypoxia (SpO2<94% using nasal 4l O2 inhale) Sustained VT or VF Post-cardiopulmonary resuscitation Patients with absolute contraindications to MRI scans The patient who is not provided of the written agreement. The patient who judged a trial entry doctor to be inappropriate as an object of the final examination.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of the extent of myocardial ischemia-reperfusion injury by cardiovascular magnetic resonance imaging 30 days after acute myocardial infarction | — |
Secondary
| Measure | Time frame |
|---|---|
| Angiographic assessment of reperfision by TIMI flow grade and myocardial blush grade. Assessment of reperfusion by ST resolution comparison of prePCI and post PCI. Assessment of infarct size by creatine phosphokinase (CPK). Assessment of left ventricular failure by Killip classification. Evaluation of left ventricular ejection fraction and infarct size by cardiac MRI imaging in chronic phase. Assesment of major advance cardiac event. | — |
Countries
Japan
Contacts
Public ContactHisao Hara
National Center for Global Health and Medicine Department of Cardiology
Outcome results
None listed