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Exploratory research for role of typical protein-bound uremic toxins as a cardiorenal syndrome in patients with acute heart failure and/or acute myocardial infarction.

Exploratory research for role of typical protein-bound uremic toxins as a cardiorenal syndrome in patients with acute heart failure and/or acute myocardial infarction. - TUTORIAL-1 trail

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000014375
Enrollment
50
Registered
2014-07-01
Start date
2014-07-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute heart failure and/or acute myocardial infarction

Interventions

None listed

Sponsors

Department of Cardiovascular Medicine, Okayama Univesity Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Lead Sponsor
Department of Biopharmaceutics, School of Pharmacy, Kumamoto University
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patient with acute heart failure and/or acute myocardial infarction who had required urgent hospitalization. 2. Over 20 years old patient, regardless of sex.

Exclusion criteria

Exclusion criteria: 1. Patient who was administered investigational agent within 6 months(180 days). 2. Patient whose prognosis is regarded as less than 12 months. 3. Patient considered to be improper to this study by attending doctor

Design outcomes

Primary

MeasureTime frame
A sequence of blood concentration of typical protein-bound uremic toxins(indoxyl sulfate and p-cresyl sulfate)

Secondary

MeasureTime frame
exploratory investigation of relationship between uremic toxins and clinical events after 1 year, physical condition, and other measurements such as renal diameter, laboratory data and so on

Countries

Japan

Contacts

Public ContactKunihisa Kohno

Okayama university hospital Department of Cardiovascular Medicine

kunihisakohno@msn.com086-235-7351

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026