An Explorative Study for Metabolism of the Esophageal Epithelium in the Carcinogenic Process Using Biopsy Samples

An Explorative Study for Metabolism of the Esophageal Epithelium in the Carcinogenic Process Using Biopsy Samples - MEEB study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000014365

Enrollment

Registered

2014-06-25

Start date

2004-06-11

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

esophageal squamous cell carcinoma

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients with early esophageal squamous cell carcinoma 2) Alcohol drinker 3) Patients with non-cancerous lugol voiding lesions in the esophagus in chromo-endoscopy

Exclusion criteria

Exclusion criteria: 1) patients with history of chemotherapy 2) patients with history of radiotherapy where the esophagus was irradiated 3) patients with history of radical surgery of head and neck cancer or gastric cancer (not including local resection) 4) patients with allergy to iodine (lugol) 5) patients who are currently treated with steroid hormone

Design outcomes

Primary

Measure	Time frame
Metabolites recognized in normal epithelium, precancerous lesions and cancerous lesions, and amount of metabolites recognized in each lesion	—

Countries

Japan

Contacts

Public ContactAtsushi Yagishita

National Cancer Center East Division of science & technology for endoscopy & surgery

ayagishi@east.ncc.go.jp04-7133-1111

Outcome results