Evaluation of the effect of hepatitis B vaccines derived from different genotypes of hepatitis B viruses

Evaluation of the effect of hepatitis B vaccines derived from different genotypes of hepatitis B viruses - Evaluation of HB vaccines from different HBV genotypes

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000014363

Enrollment

150

Registered

2014-06-24

Start date

2014-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infection of hepatitis B virus

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: People whose informed consents were obtained. Sufficient amount of serum was obtained after their medical examinations.

Exclusion criteria

Exclusion criteria: Informed consents were not obtained. Sufficient amount of serum was not obtained after their medical examinations.

Design outcomes

Primary

Measure	Time frame
To detect cross-reaction of HBs antibodies in HB vaccine-immunized sera to HBs antigens from different HBV genotypes by ELISA.	—

Secondary

Measure	Time frame
To examine whether anti-HBs antibodies generated by HB vaccination protect the infection of HBV whose genotype is different from that of the immunized vaccine.	—

Countries

Japan

Contacts

Public ContactManae S. Kurokawa

St. Marianna University, Graduate School of Medicine Disease Biomarker Analysis and Molecular Regulation

manae@marianna-u.ac.jp81-44-977-8111

Outcome results