Pulmonary arteriovenous malformation
Conditions
Interventions
Following doing pulmonary arteriography, venous sac embolization of pulmonary arteriovenous mulformations is to be performed using Hydrocoil. Embolization is performed in 1 procedure.
Sponsors
Okayama University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Pulmonary arteriovenous malformation exists on chest CT (<= 3mm thickness) 2) Meets one or more following criteria. a) history of brain infarction and/or abscess b) history of transient ischemic attack c) history of hemoptysis d) history of hypoxemia e) diameter of feeding pulmonary artery >= 3mm. 3) Adequate cardiac, hepatic, renal, respiratory, coagulation, and bone marrow functions. 4) Performans status of 0-2. 5) Life expectancy >= 13 months.
Exclusion criteria
Exclusion criteria: 1) History of allergy of iodinated contrast material 2) Active asthma 3) Single lung. 4) Inpaired pulmonary function of contralateral lung. 5) Pulmonary hypertension. 6) Estimated Glomerular Filtration Rate < 30min/mil (excluding dialysis) 7) Child Pugh score >= 9 8) Heart failure (NYHA >= III) 9) Uncontrolable malignant disease. 10) Active infection or active inflammatory process 11) Body temperature of 38 degree or more. 12) Pregnant. 13) Not eligible determined by the responding physician.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| efficacy | — |
Secondary
| Measure | Time frame |
|---|---|
| adverse event image findings | — |
Countries
Japan
Contacts
Public ContactToshihiro Iguchi
Okayama University Hospital Department of Radiology
Outcome results
None listed