Longitudinal study across the spectrum of Alzheimer's disease associated with amyloid PET Imaging

Longitudinal study across the spectrum of Alzheimer's disease associated with amyloid PET Imaging - Longitudinal study across the spectrum of Alzheimer's disease associated with amyloid PET Imaging

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000014346

Enrollment

160

Registered

2014-06-24

Start date

2014-06-06

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alzheimer&#39

Interventions

Three-dimensional Dynamic PET images of the brain will be acquired for 60min after intravenous administration of [11C-PIB](about 550 mBq ).

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)The patients had underwent 11C-PIB PET in the past. 2)55years old-90years old,male and female. 3)Written informed consent was obtained from patient or his/her family.

Exclusion criteria

Exclusion criteria: 1)The past and present history of alcoholism and epilepsy 2)The past and present history of psychiatric, disorders, cerebrovascular disease, degenerative disease of the brain and head injury. 3)Severe complication including malignancy, heart failure, hepatic dysfunction, renal dysfunction, endocrine disorders, etc 4)Patients treated with antidepressants, antipsychotics,and long-term sedative-hypnotics 5)The patients that investigators need to exclude.

Design outcomes

Primary

Measure	Time frame
1)To investigate the deposits of beta-amyloid in brain cortex. 2)Degree of impairment of cognitive function correlate with beta-amyloid.	—

Countries

Japan

Contacts

Public ContactShizuo Hatashita

Shonan-Atsugi hospital Department of neurosurgery

tiken2@shonan-atsugi.jp046-297-7576

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026

Longitudinal study across the spectrum of Alzheimer&#39;s disease associated with amyloid PET Imaging