Glucocorticoid-Induced Osteoporosis
Conditions
Interventions
Denosumab
Bisphosphonate
Sponsors
Department of Connective Tissue Diseases, Tokyo Medical Center, National Hospital Organization
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Glucocorticoid administered. Less than 80% (%YAM) of bone mineral density at the lumber spine or femoral neck, or presence of fragile fracture at the spine.
Exclusion criteria
Exclusion criteria: More than one year of bisphosphontes in 2 years before entry. Contraindication against bisphosphonates and denosumab.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percent change in bone mineral density of the lumbar spine | — |
Secondary
| Measure | Time frame |
|---|---|
| Safety, Incident vertebral fracture, bone mineral density of the femoral neck, bone makers | — |
Countries
Japan
Contacts
Public ContactHisaji Oshima
Tokyo Medical Center, National Hospital Organization Department of Connective Tissue Diseases
Outcome results
None listed