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Glucocorticoid-Induced Osteoporosis Treated with Bisphosphonate and Denosumab

Glucocorticoid-Induced Osteoporosis Treated with Bisphosphonate and Denosumab - GOBID Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000014341
Enrollment
100
Registered
2014-06-23
Start date
2014-06-24
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glucocorticoid-Induced Osteoporosis

Interventions

Denosumab Bisphosphonate

Sponsors

Department of Connective Tissue Diseases, Tokyo Medical Center, National Hospital Organization
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Glucocorticoid administered. Less than 80% (%YAM) of bone mineral density at the lumber spine or femoral neck, or presence of fragile fracture at the spine.

Exclusion criteria

Exclusion criteria: More than one year of bisphosphontes in 2 years before entry. Contraindication against bisphosphonates and denosumab.

Design outcomes

Primary

MeasureTime frame
Percent change in bone mineral density of the lumbar spine

Secondary

MeasureTime frame
Safety, Incident vertebral fracture, bone mineral density of the femoral neck, bone makers

Countries

Japan

Contacts

Public ContactHisaji Oshima

Tokyo Medical Center, National Hospital Organization Department of Connective Tissue Diseases

HOhshima@ntmc-hosp.jp03-3411-0111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026