thoracic aortic aneurysm with hypertension
Conditions
Interventions
Patients with hypertension after thoracic aneurysm surgery are started to take medicines following treatment groups at the point of recovering well from surgery. The patients in treatment groups of ol
Sponsors
Department of Cardiovascular Surgery,Tohoku University School of Medicine
nothing
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with hypertension after thoracic aneurysm surgery are selected for targets of this trial and registered with this trial. We don't care about types of aneurysm and sorts of surgery.The definition of hypertension is a systolic blood pressure of more than 140 mmHg or a diastolic blood pressure of more than 90 mm Hg on the basis of hypertension guidelines
Exclusion criteria
Exclusion criteria: "Patients with thoracic aneurysm induced from congenital connective tissue disorder such as Marfan's syndrome" "Patients with thoracic aneurysm induced from autoimmune disorder such as aortitis syndrome" "Patients with chronic renal failure, which is more than 2.0mg/dL of serum creatinine concentration, or more than 2g of protein in urine daily" "Patients restricted to take olmesartan or eplerenone" "Patients during pregnancy or expecting to get pregnant" "Patients younger than 20" "Patinets refusing to anticipate this trial" "Patients which we judged unsuitable for this trial"
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| residual aortic diameter changes in contrast CT images after two years from thoracic aortic aneurysm surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| changes in CAVI(cardio ankle vascular index) plasma aldosterone concentration high-sensitive CRP blood pressure in outpatient clinic transthoracic echocardiogram renal function | — |
Countries
Japan
Contacts
Public ContactKiichirou Kumagai
Tohoku University School of Medicine Dept. Cardiovascular Surgery
Outcome results
None listed