High flow nasal cannula versus venturi mask for cardiovascular surgical patients after endotracheal extubation: A randomized crossover study

High flow nasal cannula versus venturi mask for cardiovascular surgical patients after endotracheal extubation: A randomized crossover study - High flow nasal cannula versus venturi mask for cardiovascular surgical patients after endotracheal extubation.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000014241

Enrollment

Registered

2014-06-11

Start date

2014-06-11

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patient who underwent cardiovascular surgery

Interventions

Protocol A (venturi mask for an hour followed by high flow nasal cannula for an hour) Protocol B (high flow nasal cannula for an hour followed by venturi mask for an hour)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patient scheduled cardiovascular surgery (valvular surgery and coronary artery bypass grafting with median sternotomy using cardiopulmonary bypass.

Exclusion criteria

Exclusion criteria: Patient who has chronic obstructive lung disease and chronic renal failure. Patient who requires more than 24 hours until extubation. Emergent surgery.

Design outcomes

Primary

Measure	Time frame
Arterial blood gas analysis (PaO2,PaCO2,pH,HCO3-)	—

Secondary

Measure	Time frame
Physiologic data (respiratory rate, heart rate, blood pressure, cardiac index, mixed venous oxygen saturation), and patient comfort.	—

Countries

Japan

Contacts

Public ContactYusuke Kusaka

Osaka medical College Department of intensive care medicine

Y.kusaka1978@gmail.com+81-72-683-1221

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026