urothelial carcinoma of upper urinary tract
Conditions
Interventions
neoadjuvant chemotherapy plus radical nephroureterectomy
radical nephroureterectomy
Sponsors
the Department of Urology, Graduate School of Medicine, Kyoto University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1 clinical diagonosis of invasive urothelial carcinoma of upper urinary tract (cT2-4 or cTxN+) by imaging and urinary cytology 2 cases without unresectable distant metastasis 3 cases that an radical operation under the general anesthesia is possible. 4 cases with primary urothelial carcinoma (cases with hirtory of non-muscle invasive bladder cancer can be registered.) 5 Performance status 0-1 6 Cases maintaining the functions of the main organs.
Exclusion criteria
Exclusion criteria: 1 Pregnant or potentially women, nursing women 2 Patients with past history of radicalcystectomy 3 Patients with psychiatric diseases 4 Patients with severe or complicated medical conditions, not allowing participation into this protocol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 3-year disease-free survival rate | — |
Countries
Japan
Contacts
Public ContactYoshiyuki Matsui
Graduate School of Medicine, Kyoto University the Department of Urology
Outcome results
None listed