Effect of Lactobacillus brevis KB290 on constipation and on microbiota of people who tend to be constipated.

Effect of Lactobacillus brevis KB290 on constipation and on microbiota of people who tend to be constipated. - Effect of Lactobacillus brevis KB290 on constipation and on microbiota of people who tend to be constipated.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000014085

Enrollment

Registered

2014-05-30

Start date

2014-05-30

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

people tend to be constipated

Interventions

Lactic acid beverage containing Lactobacillus brevis KB290 Placebo beverage

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: People who meet either of the following conditions will be required. 1)Whose defecation frequency is no fewer than 2, nor more than 5. 2)Whose appearance frequency of hard stool (stools which match Bristol scale score 1, 2 or 3) is 50% and over.

Exclusion criteria

Exclusion criteria: People who meet any of the following conditions will be excluded. 1)Who is judged as unsuitable because of having suffered a serious disease so far. 2)Who takes any kind of medicine which affect the result of the trial for habitual use. 3)Who has undergone surgery accompanied with digestive tract ablation. 4)Who has participated in another clinical trial within 1 month. 5)Who is judged unsuitable for this study by principal investigator.

Design outcomes

Primary

Measure	Time frame
Defecation frequency, days of defecation frequency in a week, amount of defecation, hardness of stool and amount of organic acid in stool will be measured. Also, the amount of bacteria related with bowel movement, which are Bacteroidaceae, Enterobacteriaceae, Streptococcaceae, Bifidobacterium genus, Eubacterium genus, Peptostreptococcus genus, Lactobacillus genus, Clostridium perfringens and other bacteria belongs to Clostridium genus, will be measured.	—

Measure

Time frame

Defecation frequency, days of defecation frequency in a week, amount of defecation, hardness of stool and amount of organic acid in stool will be measured. Also, the amount of bacteria related with bowel movement, which are Bacteroidaceae, Enterobacteriaceae, Streptococcaceae, Bifidobacterium genus, Eubacterium genus, Peptostreptococcus genus, Lactobacillus genus, Clostridium perfringens and other bacteria belongs to Clostridium genus, will be measured.

—

Countries

Japan

Contacts

Public ContactAkira Kobayashi

Kagome Co., Ltd. Research & Development Division

Akira_Kobayashi@kagome.co.jp0287-36-2935

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026