Salivary gland carcinoma
Conditions
Interventions
Adjuvant chemotherapy (TS-1, one year)
no adjuvant chemotherapy
Sponsors
Department of Dentistry and Oral Surgery, Shinshu University School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Proven salivary gland carcinoma 2) Having primary site in the oral and maxillofacial region excepting the parotid gland 3) Patients who underwent radical treatment with surgery 4) No evidence of distant metastasis 5) 20 years <=, <= 80 years old 6) ECOG performance status 0 or 1 7) Registration within 3 months after the primary treatment 8) No previous chemo- or radiotherapy (excepting salivary Ca). 9) Good and fair condition of major organs. 10) Possible of oral administration 11) Written informed consent.
Exclusion criteria
Exclusion criteria: 1) The possibility (will) of the pregnancy and nursing girl 2) Active multiple primary 3) Having a mental disorder 4) Having a serious or life-threatening disease. 5) Having uncontrolled diarrhea 6) Systemic steroid use 7) Having infection 8) Having fever up over 38 degree Celsius 9) Severe allergic reaction for any drugs 10) Taking flucytosine 11) Patients who need flucytosine, phenytoin, or warfarin. 12) Anyone who was judged as unsuitable for this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall survival time | — |
Secondary
| Measure | Time frame |
|---|---|
| Disease free survival time, Distant metastasis free survival time, adverse effect | — |
Countries
Japan
Contacts
Public ContactHiroshi Kurita
Shinshu University School of Medicine Department of Dentistry and Oral Surgery
Outcome results
None listed