ST-segment elevation myocardial infarction (STEMI) treated with primary PCI
Conditions
Interventions
None listed
Sponsors
Department of Cardiology, Niigata City General Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Patients with STEMI within 24hours from onset amenable to primary PCI. 2)Age: 20 years old or more. 3)Regardless of glycemic profile.
Exclusion criteria
Exclusion criteria: 1)Patients suspected to have type 1 diabetes 2)Pregnant or child-bearing potential woman 3)Inability to provide informed consent 4)Patients with history of previous myocardial infarction 5)Poor recording of electrocardiography unsuitable for analysis 6)Cardiogenic shock receiving mechanical circulatory and respiratory support device
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the relationship between the mean amplitude of glycemic excursions (MAGE) and the following surrogate endpoints of ischemia reperfusion injury: ST-segment resolution (STR) and QRS score, and corrected TIMI frame count(cTFC). | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate the relationship between other glycemic parameters (HbA1c, HOMA-R) and the following surrogate endpoints of ischemic reperfusion injury: STR, QRS score, and cTFC. Clinical outcomes including death, recurrent MI, stroke, heart failure or any repeat revascularization at 30 days and 12 months as well as angiographic outcomes at 12 months. | — |
Countries
Japan
Contacts
Public ContactKeiichi Tsuchida
Niigata City General Hospital Department of Cardiology
Outcome results
None listed