Detection of intraoperative bacterial translocation in patients who undergo hepatectomy with extrahepatic bile duct resection or pancreatoduodenectomy.

Detection of intraoperative bacterial translocation in patients who undergo hepatectomy with extrahepatic bile duct resection or pancreatoduodenectomy. - Detection of intraoperative bacterial translocation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000013987

Enrollment

Registered

2014-05-20

Start date

2014-05-20

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The patients who are going to undergo hepatectomy (excluding laparoscopic surgery) and pancreatoduodenectomy.

Interventions

Intraoperative sampling of portal venous blood and mesenteric lymph nodes.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients who are going to undergo hepatectomy with extrahepatic bile duct resection or pancreatoduodenectomy. 2) Patients who agreed with participation. 3) Patients who do not have severe organ dysfunction.

Exclusion criteria

Exclusion criteria: 1) Patients who do not agree with participation. 2) Emergent surgery. 3) Patients who do have severe organ dysfunction. 4) Patients who have severe coagulopathy. 5) Patients who are evaluated inappropriate to participate the study by doctors.

Design outcomes

Primary

Measure	Time frame
Presence of bacterium and (if present) amount of bacterium in the portal venous blood, mesenteric lymph nodes, and peripheral blood samples.	—

Secondary

Measure	Time frame
Correlation between the incidense of intraoperative bacterial translocation and inflammatory response on POD1, the incidense of postoperative infectious complicatoins, postoperative hospital stay, and the incidense of surgery-related death.	—

Countries

Japan

Contacts

Public ContactYukihiro Yokoyama

Nagoya University Graduate School of Medicine Department of Surgery, Division of Surgical Oncology

yyoko@med.nagoya-u.ac.jp052-744-2222

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026