Acute coronary syndrome
Conditions
Interventions
None listed
Sponsors
Department of Cardiology, Kansai Electric Power Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients who visit the emergency department with a chief symptom of chest pain (newly onset, rest onset, and/or worsening) for 24 hours or less and are judged to meet all of the following conditions by the attending physician are enrolled in this trial. 1) Patients who are 20 years of age or older on the day informed consent is obtained (no upper age limit) 2) Patients with no significant ST elevation or abnormal Q waves on ECG 3) Patients with no systolic wall motion abnormalities
Exclusion criteria
Exclusion criteria: Patients who meet any one of the following conditions are excluded from the trial. 1) Patients who show signs of moderate congestive heart failure (NYHA III or higher) 2) Patients who are in shock 3) Patients with LVEF less than 50% 4) Patients with left bundle branch block 5) Patients with a history of myocardial infarction or other myocardial disease 6) Patients with valvular heart disease for which invasive treatment is judged to be necessary 7) Patients in whom acceptable ultrasound images cannot be obtained 8) Patients who are found to have abnormal cardiac wall contraction by echocardiography 9) Patients with atrial fibrillation 10) Patients with a heart rate of 40 bpm or less or 100 bpm or higher 11) Patients with a serum creatinine level of 2.0 or higher 12) Patients with a history of allergy to contrast medium 13) Patients who are pregnant or breastfeeding, patients who may be pregnant 14) Patients who should be excluded from the trial for medical reasons, based on the judgment of their attending physician
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Using the final diagnosis of ACS (truth standard) as the true value (sick or healthy), sensitivity is assessed for each of the three protocols: (1) combination of initial diagnosis and 2D speckle tracking echocardiography (Index + 2DST method), (2) initial diagnosis alone (Index method), and (3) 2D speckle tracking echocardiography alone (2DST method). | — |
Secondary
| Measure | Time frame |
|---|---|
| specificity, positive predictive value, and negative predictive value of above. | — |
Countries
Japan
Contacts
Public ContactHyodo, Eiichi
Nishinomiya Watanabe Cardiovascular Center Division of Cardiology
Outcome results
None listed