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Effect of inhaled corticosteroid therapy in pulmonary sarcoidosis patients who manifest airflow limitation

Effect of inhaled corticosteroid therapy in pulmonary sarcoidosis patients who manifest airflow limitation - Effect of inhaled corticosteroid therapy on pulmonary sarcoidosis

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000013831
Enrollment
40
Registered
2014-04-30
Start date
2014-04-30
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary sarcoidosis patients who revealed airflow limitation in peak flow tests, increased respiratory resistance in IOS, or increased WA% in HRCT.

Interventions

inhaled ciclesonide (400maicrogram, twice daily, for three months)

Sponsors

Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. patients with the definite diagnosis established when the clinicoradiologic findings were supported by the histologic evidence of noncaseating epitheloid cell granulomas and exclusion of other diseases capable of producing similar histologic or clinical features. 2. patients whose FEV1/FVC is under 80%, whose R5-R20 score is over 0.03, or whose WA% is over 55%. 3. patients over 20 years old who can give the documents which agree in participating this study

Exclusion criteria

Exclusion criteria: 1. patients with heart failure 2. patients with renal failure 3. patients with past hisotry of bronchial asthma 4. ex, or current smokers 5. patients with pulmonary disease except for pulmonary sarcoidosis 6. patients whose participations in this study are thought to be inappropriate.

Design outcomes

Primary

MeasureTime frame
To evaluate the influence of inhaled ciclesonide (400maicrogram, twice daily, for three months) on pulmonary function tests, impulse oscillometry system (IOS) and HRCT of pulmonary sarcoidosis patients.

Countries

Japan

Contacts

Public ContactToshio Suzuki

Graduate School of Medicine, Chiba University, Chiba, Japan Department of Respirology

toshiosuzuki@chiba-u.jp043-226-2800

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026