Effect of preoperative steroids administration in laparoscopic hepatectomy with pedicle clamping: a prospective randomized study

Effect of preoperative steroids administration in laparoscopic hepatectomy with pedicle clamping: a prospective randomized study - RCT to evaluate steroids administration in laparoscopic hepatectomy with pedicle clamping

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000013823

Enrollment

100

Registered

2014-04-28

Start date

2014-04-30

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diseases planned to undergo laparoscopic liver resection(malignant/benign tumor, benign diseases)

Interventions

The patients are assigned randomly to a control group or a steroid group in which patients received 500mg of methylprednisolone at induction. Administration only saline solution.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who were planned to undergo pure laparoscopic liver resection, and their performance status were 0 or 1.

Exclusion criteria

Exclusion criteria: Difficult to undergo a surgery under general anesthesia. Patients with active infection, with uncontrollable diabetes mellitus, in pregnancy, or under 20-year-old.

Design outcomes

Primary

Measure	Time frame
Serum total bilirubin level	—

Secondary

Measure	Time frame
Serum AST, ALT, PPT-INR, CRP,and IL-6 levels . Postoperative complications and length of hospital stay.	—

Countries

Japan

Contacts

Public ContactYasushi Hasegawa

Iwate Medical University School of Medicine Department of Surgery

hasegawayas@yahoo.co.jp019-651-5111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026