Freqency of Carnitine Deficiency in Patients with Chronic Liver Disease, and Efficacy of Oral L-Carnitine Treatment for Patiens with Liver Cirrhosis

Freqency of Carnitine Deficiency in Patients with Chronic Liver Disease, and Efficacy of Oral L-Carnitine Treatment for Patiens with Liver Cirrhosis - Freqency of Carnitine Deficiency in Patients with Chronic Liver Disease, and Efficacy of Oral L-Carnitine Treatment for Patiens with Liver Cirrhosis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000013787

Enrollment

Registered

2014-04-24

Start date

2012-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Simple fatty liver, non-alcohoic steatohepatitis, alcoholic liver disease, and liver cirrhosis

Interventions

L-carnitine 600mg P.O. three times per day, dietary counselling and exercise counselling for 12 weeks dietary and exercise counselling for 12 weeks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Histologically proven or clinically diagnosed liver cirrhosis,chronic liver disease (excluded viral hepatitis), and healthy volunteer 2) Written informed consent 3) Patient's age ranges from 20 to 85 years, and healthy volunteer.

Exclusion criteria

Exclusion criteria: 1) Pregnant and lactating females 2) Hisotry of drug allergy 3) Inappropriate for entry onto this study in the judgment of the investigator 4) Administration of other test drugs within 1 month

Design outcomes

Primary

Measure	Time frame
1st step: To evaluate the serum levels of carnitin between healthy volunteer and non-viral chronic liver desease. 2nd step: To evaluate the improvement of liver function with non-viral liver cirrhosis.	—

Countries

Japan

Contacts

Public ContactSANDO Takehiro

Hoshigaoka Medical Center Department of Gastroenterology and Hepatology

sando@takepapi.com072-640-2641

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026