schzophrenia
Conditions
Interventions
The aripiprazole administrated group performs a change form medicine before intervention within three months and does it with the single administration.A period is 12 months and starts at 6-12mg/day a
Sponsors
Division of Neuropsychiatry, Department of Brain and Neuroscience, Faculty of Medecine, Tottori University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: A participant is the patient who has a diagnosis of schizophrenia or schizoaffective disorder in DSM-4 or DSM-5, and used antipsychotic drug is within 1200mg/day by CP conversion, and has more than 70 estimated IQ before onset by JART.
Exclusion criteria
Exclusion criteria: The person who has a different mental disease in DSM-4 or DSM-5. A person with strong suicidal ideation and material-dependent past. A person with the past of the disease of brain tissues such as a severe head injury, the cerebrovascular disorder. A person with the past of physically serious medical history. A person with the past of daibetes. A pregnant person or a person with the pregnancy possibility and lactating. The person who uses a long-term acting antiphychotic drug(depot preparation) within three weeks before intervention. The person who is forbidden to use aripiprazole or risperidone on an appended paper.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| neuropsychological test(BACS), assessment of subjective wellbeing(SWNS-J), QOL/evaluztion of social life function(SF-36) | — |
Secondary
| Measure | Time frame |
|---|---|
| sympton evaluation(PANSS, CGI), extrapyramidal system side efffect evaluation(DIEPSS), NIRS, ERP, fMRI | — |
Countries
Japan
Contacts
Public ContactTakahiro Satake
Tottori University Division of Neuropsychiatry, Department of Brain and Neuroscience, Faculty of Medecine
Outcome results
None listed