Soluble CD14 subtype (presepsin) levels in the scheduled high-risk surgery patients who candidates ICU admission ; a prospective observational study

Soluble CD14 subtype (presepsin) levels in the scheduled high-risk surgery patients who candidates ICU admission ; a prospective observational study - Soluble CD14 subtype (presepsin) levels in the scheduled high-risk surgery patients

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000013748

Enrollment

150

Registered

2014-04-21

Start date

2014-04-21

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

the scheduled high-risk surgery patients

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The scheduled high-risk surgery patients who candidates ICU admission

Exclusion criteria

Exclusion criteria: (1)Predict infectious disease before surgery. (2)Emergency surgical patients. (3)Patients who are judged as inappropriate candidates for the trial by the investigators on preoperative anesthetic consultation. (4)Patients who are exposed to infection factor during the operation.

Design outcomes

Primary

Measure	Time frame
To verify that the level of presepsin and procalcitonin (PCT) in candidates for admission to ICU could not be changed by the high-risk operation.	—

Secondary

Measure	Time frame
(1) Evaluation of presepsin and PCT levels differ depending on operative procedure (Operative methods or cardiopulmonary bypass surgery). (2) Evaluation of presepsin and PCT levels according to severity of the disease in ICU patients. (3) Study of an influencing factor of level of presepsin and PCT. (4) Relationship between survival rate (at Day 28, 60, 90) and levels of presepsin and PCT. (5) The time course of changes in presepsin and PCT levels.	—

Measure

Time frame

(1) Evaluation of presepsin and PCT levels differ depending on operative procedure (Operative methods or cardiopulmonary bypass surgery). (2) Evaluation of presepsin and PCT levels according to severity of the disease in ICU patients. (3) Study of an influencing factor of level of presepsin and PCT. (4) Relationship between survival rate (at Day 28, 60, 90) and levels of presepsin and PCT. (5) The time course of changes in presepsin and PCT levels.

—

Countries

Japan

Contacts

Public ContactYoshitaka Hara

Fujita Health University School of Medicine Department of Anesthesiology and Critical Care Medicine

harahara19801201@yahoo.co.jp0562-93-9008

Outcome results