Evaluation of the efficacy and safety of local steroid injection and general steroid intake for prevention of post-ESD esophageal stenosis

Evaluation of the efficacy and safety of local steroid injection and general steroid intake for prevention of post-ESD esophageal stenosis - Evaluation of steroid administration for prevention of post-ESD esophageal stenosis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000013740

Enrollment

Registered

2014-05-09

Start date

2014-05-09

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Superficial esophageal cancer

Interventions

Local steroid injection and general steroid intake Local steroid injection alone

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with superficial esophageal cancer whose mucosal defect after ESD is expected to be over three-fourths of the whole circumference

Exclusion criteria

Exclusion criteria: Recurrent case. Patients with previous radiotherapy. Patients with serious cardiovascular or pulmonary disease, renal dysfunction, liver dysfunction and endocrine metabolic disorder. Patient who have been judged as inappropriate for this study.

Design outcomes

Primary

Measure	Time frame
The proportion of patients who complain dysphagia or have esophageal stricture for endoscope not enough to pass through	—

Secondary

Measure	Time frame
The frequency of the complication related to steroid administration	—

Countries

Japan

Contacts

Public ContactNonaka Takashi

Yokohama City University Hospital Department of Gastroenterology and Hepatology

nonaka@yokohama-cu.ac.jp045-787-2640

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026