Clinical significance of coronary artery molecular imaging by 18F-labeled sodium fluoride positron emission tomography -comparison and combination with coronary computed tomography angiography

Clinical significance of coronary artery molecular imaging by 18F-labeled sodium fluoride positron emission tomography -comparison and combination with coronary computed tomography angiography - Coronary artery molecular imaging by NaF PET

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000013735

Enrollment

100

Registered

2014-04-17

Start date

2014-04-17

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coronary artery disease

Interventions

coronary CT, 18F-NaF PET

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) patients aged >= 30 years old 2) patients with clearly-distinguishable calcified and/or non-calcified and/or mixed coronary plaques on CT images of coronary arteries (diameter >=2-mm) 3) patients who agree with informed consent

Exclusion criteria

Exclusion criteria: 1) acute coronary syndrome, critical heart failure 2) shock status 3) nonconciousness

Design outcomes

Primary

Measure	Time frame
1) Comparison with coronary CT findings (presence and characteristics of coronary calcium and mix or non-calcified coronary plaques) and 18-F NaF PET signal (presence and intensity) 2) potential of step-by-step approach using coronary CT and 18F-NaF PET to predict the cardiac hard events (cardiac death and acute coronary syndrome)	—

Countries

Japan

Contacts

Public ContactToshiro Kitagawa

Hiroshima University Graduate School of Biomedical and Health Sciences Cardiovascular Medicine

toshirok@hiroshima-u.ac.jp082-257-5540

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026