Placebo-controlled randomized trial on the saliva secretion effect of interferential current stimulation

Placebo-controlled randomized trial on the saliva secretion effect of interferential current stimulation - Saliva secretion effect of interferential current stimulation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000013731

Enrollment

Registered

2014-04-21

Start date

2014-04-21

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy subjects and patients with xerostomia

Interventions

placement of electrodes only interferential current stimulation

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Young adults aged between 20 - 30 years old who do not receive any medication. Elder adults aged between 50 and 90 years old who do not receive medication that reduces saliva secretion. Saliva production of patients with xerostomia, who administer the department of dentistry and oral & maxillofacial surgery, is quantified by the Saxon test; patients with the saliva volume less than 2g are eligeable for the study.

Exclusion criteria

Exclusion criteria: 1. Those who have apparent cognitive impairment (MMSE < 20) 2. Patients with ataxia or dyskinesia 3. Patients who experienced apparent aspiration pneumonia or asphyxia twice within the past two years 4. Those who are judged by a doctor as inappropriate candidates

Design outcomes

Primary

Measure	Time frame
Amount of secreted saliva	—

Secondary

Measure	Time frame
Cortisol concentration in saliva	—

Countries

Japan

Contacts

Public ContactYoko Hasegawa

Hyogo College of Medicine Department of Dentistry and Oral & Maxillofacial Surgery

cem17150@hyo-med.ac.jp0798-45-6677

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026