Hemodialysis patients with Helicobacter pylori gastritis
Conditions
Interventions
None listed
Sponsors
Division of Clinical Nephrology & Rheumatology, Niigata University Graduate School of Medical & Dental Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients of CKD stage G4 ~ 5 (eGFR <= 30, including hemodialysis patients 2) Patients were revealed as chronic gastritis by upper gastrointestinal fiberscopy 2) Outpatients with relatively stable renal function. 3) Patients who can take medication orally. 4) Patients who can receive blood tests. 5) Patients that agreed to diagnosis and treatment of H.pyroli. 6) Men and women aged over 20 years old
Exclusion criteria
Exclusion criteria: 1) Patients with a history of hypersensitivity for amoxicillin, clarithromycin, proton pump inhibitors, or metronidazole. 2) Of the patients with CKD, the patient being predicted for initiating dialysis within six months. 3) Patients complicated with acute inflammatory disease or active infection. 4) Patients with active malignant tumor. 5) Patients who suspected of being pregnant or pregnancy. 6) Patients did not make a consent for test and/or treatment of H. pyroli gastritis. 7) Patients was determined to be difficult to continue the eradication therapy by serious adverse events. 8) Patients offer discontinuation of the study. 9) Attending physician deems the patients as unsuitable of the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Eradication rate for Helicobacter pyroli | — |
Secondary
| Measure | Time frame |
|---|---|
| Sensitivity and specificity of anti-Helicobacter pylori Antibody-IgG, Dry weight during dialysis, blood pressure, body weight, chest X-ray CTR, hemoglobin, dose of ESA, serum iron, UIBC (not to TIBC), ferritin, CRP. | — |
Countries
Japan
Contacts
Public ContactYuichi SAKAMAKI
Niigata University Graduate School of Medical & Dental Sciences Division of Clinical Nephrology & Rheumatology
Outcome results
None listed