Severity scores for predicting mortality, risk factors for drug-resistant pathogens, and the sputum Gram stain test in nursing and health care-associated pneumonia: an observational study

Severity scores for predicting mortality, risk factors for drug-resistant pathogens, and the sputum Gram stain test in nursing and health care-associated pneumonia: an observational study - An observational study of nursing and health care-associated pneumonia

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000013648

Enrollment

500

Registered

2014-04-05

Start date

2014-04-05

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nursing and healthcare-associated pneumonia

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Newly diagnosed pneumonia meeting at least one of the following criteria (from a through e, see below), where pneumonia is defined as 1) the presence of a new infiltrate on a chest radiograph plus at least one of the following sumptoms or signs: fever (temperature >38.0 Celsius) or hypothermia (temperature <35.0 Celsius), new cough with or without sputum production, pleuritic chest pain, dyspnea, and altered breath sounds on auscultation (Carratala et al, Ann Intern Med 2005). 2. Criteria a. Hospitalization for at least 2 days within 90 days prior to the onset of pneumonia b. Residence in a nursing home or long-term care facility c. Taking outpatient intravenous therapy (antibiotics, chemotherapy, immunosuppressive drugs, etc.) d. Undergoing chronic dialysis treatment e. Disabled or elderly people in poor performance status (ECOG PS 3 and 4) 3. Agreeing to participate the study 4. Provision of a signed Written Informed Consent

Exclusion criteria

Exclusion criteria: Not agreeing to participate the study

Design outcomes

Primary

Measure	Time frame
Model performance (discrimination and calibration) of A-DROP, a proposed pneumonia severity score for predicting 30-day mortality	—

Secondary

Measure	Time frame
1) Model performance (discrimination and calibration) of other proposed pneumonia severity scores (PSI, C(U)RB-65) for predicting 30-day mortality 2) Predictive ability of proposed risk factors or model performance of proposed indexes for predicting drug-resistant pathogens 3) Percent of change in the selection of first-line antibiotic regimens (from empirical regimens to the Gram stain test-based focussed/narrower regimens) 4) The impact of the Gram stain test upon primary treatment failure, 30-day mortality, and 100-day mortality	—

Measure

Time frame

1) Model performance (discrimination and calibration) of other proposed pneumonia severity scores (PSI, C(U)RB-65) for predicting 30-day mortality 2) Predictive ability of proposed risk factors or model performance of proposed indexes for predicting drug-resistant pathogens 3) Percent of change in the selection of first-line antibiotic regimens (from empirical regimens to the Gram stain test-based focussed/narrower regimens) 4) The impact of the Gram stain test upon primary treatment failure, 30-day mortality, and 100-day mortality

—

Countries

Japan

Contacts

Public ContactTeruhiko Terasawa

Fujita Health University School of Medicine Department of Emergency and General Internal Medicine

terasawa@fujita-hu.ac.jp0562-93-2355

Outcome results