Effects of an acidic enteral formula containing two types of prebiotics on the intestinal environment and the antibody titers in enterally fed patients: an open-label, randomized controlled trial

Effects of an acidic enteral formula containing two types of prebiotics on the intestinal environment and the antibody titers in enterally fed patients: an open-label, randomized controlled trial - Effects of an acidic enteral formula containing prebiotics on the intestinal environment and acquired immunity

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000013593

Enrollment

Registered

2014-04-14

Start date

2010-10-26

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

influenza, diarrhea, constipation

Interventions

C group

enterally fed patients receiving a standard enteral formula over a 14-week intervention period and a 4-week follow-up period F group

enterally fed patients receiving an acidic enteral formula containing lactic acid bacteria fermented milk product, BGS and galactooligosaccharides during the 14-week intervention period, and then cons

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: hospitalized patients receiving enteral feeding in Fukushimura Hospital

Exclusion criteria

Exclusion criteria: 1. patients with gastrointestinal disorders such as diarrhea, diabetes, nephropathy, severe infection, autoimmune disease, immunodeficiency, hepatic failure, and cow's milk allergy or soybean allergy. 2. other patients judged as inappropriate for the study by the physician in charge.

Design outcomes

Primary

Measure	Time frame
antibody titers after influenza vaccination, fecal microflora and stool form consistency during the study period	—

Secondary

Measure	Time frame
blood cytokine levels during the study period	—

Countries

Japan

Contacts

Public ContactHiroyasu Akatsu

Fukushimura Hospital Choju Medical Institute

akatu@chojuken.net0532-46-7511

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026