unruptured cerebral aneurysm
Conditions
Interventions
None listed
Sponsors
National Hospital Organization
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: unruptured saccular cerebral aneurysms more than 2mm
Exclusion criteria
Exclusion criteria: dissecting cerebral aneurysm bacterial cerebral aneurysm cerebral aneurysm treated with clipping surgery and/or coil embolization the case that examinations of contrast radiography are not possible due to any reason, such as contrast media allergy, renal impairment, and/or pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Distributions of hemodynamic factors, including normalized wall shear stress, wall shear stress gradient, oscillatory shear index, gradient oscillatory number, are evaluated among the ruptured aneurysm group, the enlarged aneurysm group, and the non-ruptured & non-enlarged aneurysm group. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. In order to clarify the effect of hemodynamic factors on aneurysm growth, we virtually reconstruct arterial geometry of human cerebral aneurysms just before the development of aneurysms by artificial removal of the aneurysm, and compare values of hemodynamic factors between aneurysm-developed side and non-developed normal side. 2. Modified Rankin Scales are evaluated between the surgical group and the non-surgical group. | — |
Countries
Japan
Contacts
Public ContactShunichi Fukuda
National Hospital Organization Kyoto Medical Center Department of Neurosurgery
Outcome results
None listed