Time course of change in venous concentration of locally infiltrated morphine during total knee arthroplasty

Time course of change in venous concentration of locally infiltrated morphine during total knee arthroplasty - Venous morphine concentration after knee infiltration

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000013576

Enrollment

Registered

2014-04-01

Start date

2014-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

osteoarthritis of the knee

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: ASA physical status 1 or 2 receive total knee arthroplasty with general anesthesia serum hemoglobin 10g/dl or more operation performed by the specific operator

Exclusion criteria

Exclusion criteria: ASA physical status 3 or more renal dysfunction (CKD stage3 or more) cognitive dysfunction known allergy to the drugs diabetes mellitus BMI35 or more Rheumatic arthritis

Design outcomes

Primary

Measure	Time frame
measurement of venous concentration of morphine hydrochloride and its metabolites	—

Secondary

Measure	Time frame
measurement of postoperative pain scores and evalutation of incidence of opioid related side-effects.	—

Countries

Japan

Contacts

Public ContactYohei Fujimoto

Osaka City University, Graduate school of medicine. Department of anesthesiology

yohei7@hera.eonet.ne.jp06-6645-2186

Outcome results