Functional Dyspepsia
Conditions
Interventions
Acotiamide Hydrochloride
Placebo
Sponsors
Hyogo College of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Outpatients who are at least 20 years of age. 2. Patients with at least one of the following symptoms. -Bothersome postprandial fullness after eating a normal amount of food that occurs at least twice a week. -Unable to finish a normal amount of food due to early satiation at least twice a week. 3. Patients with symptom onset at least 6 months before the visit who meet the above criteria over the last 3 months. 4. Patients who undergo upper gastrointestinal endoscopy within 1 year from the visit and are found to have no organic diseases (malignant tumors, peptic ulcer, esophagitis, etc.) that are likely to cause upper abdominal symptoms.
Exclusion criteria
Exclusion criteria: 1. Patients with conditions that are likely to cause upper abdominal symptoms such as malignant tumors, peptic ulcers and systemic diseases (neurological diseases including Parkinson's disease, metabolic diseases including diabetes, etc). 2. Patients with known causes of upper abdominal symptoms including excessive drinking, overeating, taking NSAIDs, and sever stress. 3. Patients with predominant GERD 4. Patients with predominant irritable bowel syndrome (IBS) 5. Patients with a history of surgery of the upper gastrointestinal tract including the stomach and esophagus.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gastric emptying (T1/2) and accommodation (%) by gastric scintigraphy | — |
Countries
Japan
Contacts
Public ContactTadayuki Oshima
Hyogo College of Medicine Division of Gastroenterology, Department of Internal Medicine
Outcome results
None listed