Juntendo the Stroke Prevention study in Insulin Resistance and Impaired glucose Tolerance (J-SPIRIT study)

Juntendo the Stroke Prevention study in Insulin Resistance and Impaired glucose Tolerance (J-SPIRIT study) - The efficacy of pioglitazone for secodary prevention of ischemic stroke

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000013499

Enrollment

200

Registered

2014-03-24

Start date

2005-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

symptomatic ischemic stroke or transient ischemic attacak (TIA)

Interventions

with pioglitazone without pioglitazone

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Symptomatic ischemic stroke or transient ischemic attack (TIA) 2. modified Ranking Scale&#8804;3 3. The patients without the diagnosis of diabetes mellitus or without taking any anti diabetics, received 75g OGTT, and show any abnomral glucose metabolism such as IFG, or IGT, or diabetes mellitus

Exclusion criteria

Exclusion criteria: 1. patinents with bleeding 2. patients with pregnant or its possibility 3. severe renal dysfunction or liver dysfunction 4. allergy against alogliptin 5. can not receive informed concent 6. inappropriate for this study

Design outcomes

Primary

Measure	Time frame
recurrence of ischemic stroke	—

Countries

Japan

Contacts

Public ContactRyota Tanaka

Juntendo University School of Medicine Department of Neurology

r_tanaka@juntendo.ac.jp03-3813-3111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026