Evaluation of remineralization of root caries by application of nanoseal.

Evaluation of remineralization of root caries by application of nanoseal. - Root caries remineralization by nanoseal.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000013463

Enrollment

129

Registered

2014-04-01

Start date

2014-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Root caries

Interventions

Application of nanoseal to root caries. Experimental period

6 months. Samples are devided into three groups

application every month or every 3 months for 6 months and control. Root surface cleaning in all groups. Use of tooth paste &quot

Brosal&quot

in all groups.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Root caries ranged to 40 from 1 of the diagnodent measurement. The patient performing the oral care at least once a day in the past 2 weeks.

Exclusion criteria

Exclusion criteria: Root caries applied with nanoseal previously.

Design outcomes

Primary

Measure	Time frame
The degree of mineralization of root caries after 6 months of nanoseal use (the value of Daiagnodent).	—

Secondary

Measure	Time frame
Change of mineralization, size and color of root caries in a period of 6 months.	—

Countries

Japan

Contacts

Public ContactHirofumi Miyaji

Hokkaido University Hospital Clinic of Endodontology and Periodontology

miyaji@den.hokudai.ac.jp011-706-4343

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026