Comparison of dexmedetomidine and propofol for conscious sedation in dental surgery

Comparison of dexmedetomidine and propofol for conscious sedation in dental surgery - Comparison of dexmedetomidine and propofol for conscious sedation in dental surgery

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000013448

Enrollment

Registered

2014-03-19

Start date

2014-05-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

adult patients who need intravenous sedation for dental surgery

Interventions

conscious sedation with midazolam (Dormicum) and dexmedetomidine (Precedex). conscious sedation with midazolam (Dormicum) and propofol (Diprivan).

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: adult patients who need conscious sedation for dental surgery

Exclusion criteria

Exclusion criteria: patients aged over 80; ASA physical status 3 and 4; patients with contraindications to propofol, dexmedetomidine and midazolam; allergy to soybean or egg; a history of cardiovascular or respiratory disease; use of drugs for psychotropic and cardiac desease.

Design outcomes

Primary

Measure	Time frame
unexpected patient movements	—

Secondary

Measure	Time frame
responsiveness, mouth opening time, cough reflex, snoring, total and rescue dose of midazolam, patient and operator satisfaction, memory of the procedure, recovery behaviour after sedation.	—

Countries

Japan

Contacts

Public ContactHiroshi Hanamoto

Osaka University Graduate School of Dentistry Department of Dental Anesthesia

hanamoto@dent.osaka-u.ac.jp06-6879-2972

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026