Pharmacokinetics and pharmacodynimics of intravenous acetaminophen in Japanese surgical patients

Pharmacokinetics and pharmacodynimics of intravenous acetaminophen in Japanese surgical patients - Pharmacology of intravenous acetaminophen

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000013418

Enrollment

Registered

2014-03-14

Start date

2014-03-17

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients who undergo surgeries under general anesthesia

Interventions

Control (no acetaminophen) (Pharmacokinetic analysis will be performed with 3 groups below

no control group is required) 15 min of duration of administration of intravenous acetaminophen 60 min of duration of administration of intravenous acetaminophen 120 min of duration of administration

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: ASA 1,2, and 3 Patients who undergo elective surgeries

Exclusion criteria

Exclusion criteria: 1.Known allergy to acetaminophen 2.Psychoneurotic disorders 3.Psychiatric pharmacotherapy 4.Chronic use of ACET, NSAIDs or opioids 5.Women who were pregnant or breast-feeding 6.Anemia 7.Liver or advanced renal dysfunction 8.Those who were considered inadequate

Design outcomes

Primary

Measure	Time frame
Analgesics required postoperatively	—

Countries

Japan

Contacts

Public ContactShinju Obara

Fukushima Medical University Anesthesiology

masui@fmu.ac.jp0245471342

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026