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The effects of dexmedetomidine and fentanyl on emergence agitation after sevoflurane anesthesia in children undergoing adenotonsillectomy

The effects of dexmedetomidine and fentanyl on emergence agitation after sevoflurane anesthesia in children undergoing adenotonsillectomy - The effects of dexmedetomidine and fentanyl on emergence agitation in children

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000013394
Enrollment
90
Registered
2014-03-11
Start date
2014-03-12
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adenotonsillectomy

Interventions

Control group will be infused with normal saline 10 ml throughout 10 min 6 min before anesthesia induction. Dexmedetomidine group will be infused with dexmedetomidine 2 mcg/kg + normal saline (total 1

Sponsors

Korea University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Pediatric patients aged 3~10 years with a physical status of 1 (the American Society of Anesthesiologists rating) who are scheduled to undergo elective adenotonsillectomy.

Exclusion criteria

Exclusion criteria: Patients with a history of cardiovascular, respiratory (asthma), neurologic (seizure), kidney, liver disease, mood disorder, prematurity, or developmental delay, the presence of upper respiratory infection, hypersensitivity to drugs, and those receiving analgesics, sedatives or psychiatric medication will be excluded.

Design outcomes

Primary

MeasureTime frame
Emergence agitation score (using both a 5-point sacle and a PAED scale)

Secondary

MeasureTime frame
Hemodynamics including mean blood pressure and heart rate, recovery profiles including the time to restration of self-respiration, eye opening on verbal command, and extubation

Countries

Asia(except Japan)

Contacts

Public ContactByung Gun Lim

Korea University Guro Hospital, Korea University College of Medicine Department of Anesthesiology and Pain Medicine

bglim9205@korea.ac.kr82-2-2626-1437

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026