Chronic fatigue syndrome
Conditions
Interventions
L-Cartine FF 10 % (Otsuka Pharmacy, Co.LTD., Japan), 2000 mg / day, 8 weeks
Sponsors
Osaka City University Graduate School of Medicine
Yamaguchi University, Graduate School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Chronic fatigue syndrome (CFS) patients who visit Osaka City University Hospitals, Fatigue Clinical Center and are eligible for the following criteria. (1) Patients fulfilling the CFS criteria determined by CDC (1994) (2) Patients whose diseases duration are more than 6 months and less than 15 years (3) Patients whose fatigue related performances status are equal or less than 3 (4) Patients who are less than 60 year-old and non-smokers at the time of getting the informed consent (5) Patients whose body mass index are equal or more than 16 and equal and less than 30 at the time of getting the informed consent (6) Patients who are capable of understanding the study, and those who can give written informed consents
Exclusion criteria
Exclusion criteria: (1)Patients comorbid with organic diseases which apparently induce fatigue except CFS (2)During the pregnancy or nursing, or patients to be pregnant during the study period (3)Patients who receive warfarin (4)Patients who receive carnitine (5)Others
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Chalder Fatigue Scale,Performance Status, Fatigue sensation : Visual Analog Scale | — |
Secondary
| Measure | Time frame |
|---|---|
| CES-D, POMS, Autonomic nervous system, Carnitine, Ammonia, arithmetic task, d-ROMs, BAP, sleep-wake cycle, near infrared spectrometer | — |
Countries
Japan
Contacts
Public ContactHirohiko Kuratsune
Osaka City University, Graduate School of Medicine Physiology
Outcome results
None listed